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Journal Articles
  1. Vasan S, Hurley A, Schlesinger SJ, Hannaman D, Gardiner DF, Dugin DP, Boente-Carrera M, Vittorino R, Caskey M, Andersen J, Huang Y, Cox JH, Tarragona-Fiol T, Gill DK, Cheeseman H, Clark L, Dally L, Smith C, Schmidt C, Park HH, Kopycinski JT, Gilmour J, Fast P, Bernard R, Ho DD. In vivo electroporation enhances the immunogenicity of an HIV-1 DNA vaccine candidate in healthy volunteers. PLoS One. 6(5): e19252 (2011).
    Article from Publisher
  2. Dupuy LC, Richards MJ, Ellefsen B, Chau L, Luxembourg A, Hannaman D, Livingston BD, Schmaljohn CS. A DNA vaccine for venezuelan equine encephalitis virus delivered by intramuscular electroporation elicits high levels of neutralizing antibodies in multiple animal models and provides protective immunity to mice and nonhuman primates. Clin Vaccine Immunol. 18(5): 707-716 (2011).
    Article from Publisher
  3. Liu KH, Ascenzi MA, Bellezza CA, Bezuidenhout AJ, Cote PJ, Gonzalez-Aseguinolaza G, Hannaman D, Luxembourg A, Evans CF, Tennant BC, Menne S. Electroporation Enhances Immunogenicity of a DNA Vaccine Expressing Woodchuck Hepatitis Virus Surface Antigen in Woodchucks. Journal of Virology. 85(10): 4853-4862 (2011).
    Article from Publisher
  4. Dolter KE, Evans CF, Ellefsen B, Song J, Boente-Carrera M, Vittorino R, Rosenberg TJ, Hannaman D, Vasan S. Immunogenicity, safety, biodistribution and persistence of ADVAX, a prophylactic DNA vaccine for HIV-1, delivered by in vivo electroporation. Vaccine. 29(4): 795-803 (2011).
    Article from Publisher
  5. van Drunen Littel-van den Hurk S, Hannaman D Electroporation for DNA immunization: clinical application. Expert Review of Vaccines 9(5): 503-517 (2010).
    Article from Publisher
  6. van Drunen Littel-van den Hurk S, Lawman Z, Wilson D, Luxembourg A, Ellefsen B, van den Hurk JV, Hannaman D. Electroporation enhances immune responses and protection induced by a bovine viral diarrhea virus DNA vaccine in newborn calves with maternal antibodies. Vaccine. 28(39): 6445-6454 (2010).
    Article from Publisher
  7. Tenbusch M, Grunwald T, Niezold T, Storcksdieck genannt Bonsmann M, Hannaman D, Norley S, Uberla K. Codon-optimization of the hemagglutinin gene from the novel swine origin H1N1 influenza virus has differential effects on CD4+ T-cell responses and immune effector mechanisms following DNA electroporation in mice. Vaccine. 28(19): 3273-3277 (2010).
    Article from Publisher
  8. Livingston BD, Little SF, Luxembourg A, Ellefsen B, Hannaman D. Comparative performance of a licensed anthrax vaccine versus electroporation based delivery of a PA encoding DNA vaccine in rhesus macaques. Vaccine. 28(4): 1056-1061 (2010).
    Article from Publisher
  9. Alexander J, Bilsel P, del Guercio MF, Stewart S, Marinkovic-Petrovic A, Southwood S, Crimi C, Vang L, Walker L, Ishioka G, Chitnis V, Sette A, Assarsson E, Hannaman D, Botten J, Newman MJ. Universal influenza DNA vaccine encoding conserved CD4+ T cell epitopes protects against lethal viral challenge in HLA-DR transgenic mice. Vaccine. 28(3): 664-672 (2010).
    Article from Publisher
  10. Best SR, Peng S, Juang C, Hung C, Hannaman D, Saunders JR, Wu TC, Pai SI. Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery. Vaccine. 27(40): 5450-5459 (2009).
    Article from Publisher
  11. van Drunen Littel-van den Hurk S, Luxembourg A, Ellefsen B, Wilson D, Ubach A, Hannaman D, van den Hurk JV. Electroporation-based DNA transfer enhances gene expression and immune responses to DNA vaccines in cattle. Vaccine. 26(43): 5503-5509 (2008).
    Article from Publisher
  12. Luxembourg A, Hannaman D, Nolan E, Ellefsen B, Nakamura G, Chau L, Tellez O, Little S, Bernard R. Potentiation of an anthrax DNA vaccine with electroporation. Vaccine. 26(40): 5216-22 (2008).
    Preprint Manuscript / Article from Publisher
  13. Luxembourg A, Hannaman D, Wills K, Bernard R, Tennant BC, Menne S, Cote PJ. Immunogenicity in mice and rabbits of DNA vaccines expressing woodchuck hepatitis virus antigens. Vaccine. 26(32): 4025-33 (2008).
    Preprint Manuscript / Article from Publisher
  14. Nchinda G, Kuroiwa J, Oks M, Trumpfheller C, Park CG, Huang Y, Hannaman D, Schlesinger SJ, Mizenina O, Nussenzweig MC, Uberla K, Steinman RM. The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells. Journal of Clinical Investigation. 118(4): 1427-1436 (2008).
    Article from Publisher
  15. LeBlanc R, Vasquez Y, Hannaman D, Kumar N. Markedly enhanced immunogenicity of a Pfs25 DNA-based malaria transmission-blocking vaccine by in vivo electroporation. Vaccine 26(2): 185-192 (2008).
    Article from Publisher / Author Manuscript
  16. Luxembourg A, Evans CF, Hannaman D Electroporation-based DNA immunisation: translation to the clinic. Expert Opin Biol Ther 7(11): 1647-1664 (2007).
    Article from Publisher / Email Author for Reprint
  17. Jaini R, Hannaman D, Johnson JM, Bernard RM, Altuntas CZ, de las Alas MM, Kesaraju P, Luxembourg A, Evans CF, Tuohy VK. Gene-Based Intramuscular Interferon-beta Therapy for Experimental Autoimmune Encephalomyelitis. Mol Ther 14(3): 416-422 (2006).
    Preprint Manuscript / Article from Publisher / Email Author for Reprint
  18. Luxembourg A, Hannaman D, Ellefsen B, Nakamura G, Bernard R. Enhancement of immune responses to an HBV DNA vaccine by electroporation. Vaccine 24(21): 4490-4493 (2006).
    Preprint Manuscript / Article from Publisher
Published Abstracts
  1. Luxembourg A, Hannaman D, Masterson S, Ellefsen B, Nakamura G, Bernard R. Potentiation of DNA vaccination using an integrated application system for electroporation-mediated intramuscular delivery. Molecular Therapy 11 (Supplt 1), pp S215-S216 (2005).
  2. Evans C, de las Alas M, Nolan E, Luxembourg A, Hannaman D, Nakamura G, Ellefsen B, Bernard R. Electroporation-Mediated IFN-β Gene Transfer, Molecular Therapy 9 (Supplt 1), pp S56 (2004).
  3. de las Alas M, Nolan E, Hannaman D, Nakamura G, Ellefsen B, Luxembourg A, Bernard R. Electroporation Mediated Intramuscular Transfer of the Homologous IFN-α Gene Results in Sustained Expression and Biological Response in Mice and Rats, Molecular Therapy 7 (5), pp S379 (2003).
  4. Vilalta A, Margalith M, Parker S, Sawdey M, de las Alas M, Bernard R, Hannaman D. Electroporation of Non-Human Primate with Erythropoeitin Plasmid DNA Results in Sustained High Hematocrit with No Adverse Effects, Molecular Therapy 7 (5), pp S114 (2003).
  5. de las Alas, M, Hannaman, D, Ellefsen, B, Nakamura, G, Sawdey M, Luxembourg A, Vilalta A, Bernard R. Long-Term EPO Gene Expression in Rats Using A Clinically Relevant Dose and Electroporation System, Molecular Therapy 5 (5), pp S327 (2002).
  6. de las Alas M, Hannaman D, Ellefsen B, Nakamura G, Sawdey M, Hartikka J, Bernard R. Development of a Clinically Relevant Electroporation System for Implementation of EPO Gene Therapy, Molecular Therapy 3 (5), pp S70 (2001).
  7. Hartikka J, Bozoukova V, Sawdey M, Vilalta A, de las Alas M, Hannaman D, Ellefsen B, Bernard R, Manthorpe M. Plasmid DNA Transfection in Rat and Mouse Muscle: Effect of pDNA Dose, Injection Volume and Electroporation. Molecular Therapy 3 (5), pp S65 (2001).
Poster Presentations
  1. Gardiner D, Huang Y, Basu S, Hannaman D, Luxembourg A, Ellefsen B, Song Y, Ho D. Electroporation Significantly Enhances Cell-mediated and Humoral Immune Responses to DNA-based HIV-1 Vaccines in Animal Models, 12th Conference on Retroviruses and Opportunistic Infections, Boston, MA, Feb. 22-25, 2005.
  2. Luxembourg A, Hannaman D, Ellefsen B, Nakamura G, Bernard R. A Clinically Suitable Electroporation-based Vaccine Delivery System that Enhances Antibody and T-Cell Responses to DNA Vaccination, DNA Vaccine 2004, Monte Carlo, Monaco, Nov. 17-19, 2004.
  3. Luxembourg A, Hannaman D, Ellefsen B, Nakamura G, Bernard R. DNA Immunization by Electroporation: A promising method for therapeutic HBV vaccination, The American Association for the Study of Liver Diseases, Single Topic Conference, Immunovirology and the Liver, Warrenton, VA, Jun. 11-13, 2004.
  4. Luxembourg A, Hannaman D, Ellefsen B, Nakamura G, Bernard R. Induction of Systemic Antitumor Effects by Electroporation-Based IL-12 Gene Transfer into B16 Subcutaneous Melanoma Tumor, 56th Annual Symposium on Fundamental Cancer Research, M.D. Anderson Cancer Center, Houston, TX, Oct. 14-17, 2003.
  5. Luxembourg A, Hannaman D, Ellefsen B, Nakamura G, Bernard R. Potentiation of DNA Vaccines by Electroporation, Cancer Vaccine 2003 Symposium, Cancer Research Institute, New York, NY, Oct. 1-3, 2003.
  6. Luxembourg A, Hannaman, D, Ellefsen, B, Nakamura, G, Bernard, R. Electroporation-based combination cytokine gene therapy for melanoma treatment, Eleventh International Conference on Gene Therapy of Cancer, Coronado, CA, December 12-14, 2002.
  7. Luxembourg A, Hannaman, D, Ellefsen, B, Nakamura, G, Bernard, R. Electroporation-based DNA immunization, 8th National Symposium Basic Aspects of Vaccines, Bethesda, MD, May 1-3, 2002.
Invited Communications
  1. Hannaman D, Bernard R, de las Alas M. Delivery Technology Reenergizes DNA Drug Development, BioProcess International, Volume 6, Number 5, May 2008
  2. Hannaman D. Delivering on the Potential of DNA Vaccines, Drug Delivery Report Winter 2007/2008
  3. Luxembourg A, Hannaman D, Ellefsen B, Nakamura G, Bernard R. Potentiation of DNA Vaccines and Cancer Immunotherapy by Electroporation, 6th Annual Walker's Cay Colloquium on Cancer Vaccines and Immunotherapy, Sabin Vaccine Institute, March 10-13, 2004